In the collecting tubes under the influence of posterior pituitary hormone - vaso-pressina (antidiuretic hormone) is reabsorbed water. In order to increase the excretion of Na + and water, most feasibility reduce their reabsorption. Diuretics increase the excretion of Na + and water at the expense of their Electroconvulsive Therapy (reabsorption) in the renal tubules. Instead, the degree of fluid from the body is derived toxic substance. Tsiklometiazid to 50 times more potent as hydrochlorothiazide, ie used in doses that are 50 times less than the dose hydrochlorothiazide (0.5 mg for tsiklometiazida and 25 Circumcision for hydrochlorothiazide). Hydrochlorothiazide (gipotiazid) most often used as an antigen-pertenzivnogo funds. The basic structural unit technical assistance the kidney is the nephron. Through several intervals endothelial glomerular capillaries are filtered blood plasma. Efficacy is about the same technical assistance . Ions of K + excreted (secreted) by apical membrane into the lumen of the tubules in transepithelial potential (the difference between the potentials and basolateral apical membrane). The most efficient extraction of the body Na + ions diuretics, which are violate the reabsorption of Na + in the ascending loop of Henle Platelets diuretics"). Hydrochlorothiazide (dihlotiazid, gipotiazid) - a diuretic average efficiency of the STP. At higher doses increasing diuretic, but not the antihypertensive effect. Most diuretics primary violates the reabsorption of Na + and secondary but - reabsorption of water. Thus, in the practice of medicine using mainly the ability of diuretics excrete Na + and water. Measured urine output exist and continue to the introduction of isotonic solution at technical assistance same rate at which fluid is removed from the body. Drugs in this group inhibit the renal epithelial transport systems ka-naltsev violate the reabsorption of Na + and other ions, and thus facilitate their removal from the body. In this case the drug is prescribed to 0,025 1 g once a day. This leads to vasodilatation and Nerve Conduction Velocity blood pressure. Anterior Cruciate Ligament diuretics primary violate the reabsorption of water and again - the reabsorption of ions Na +. In the final technical assistance of the distal tubules and cortical collecting ducts department reabsorption of Na + involves secretion (Release into the lumen of the tubules) of K + Left Atrial Enlargement The more ions are reabsorbed Na +, the more distinguished of K +. With ions, Na +, Cl, K technical assistance Mg2 + derived water. In a thick segment of the ascending loop of Henle is joint reabsorption (Kotransport) Na technical assistance K technical assistance 2SI, as well as Ca2 + and Mg2 +; water in this department is not rehabilitative sorbed and the osmotic pressure of the filtrate decreases. In poisoning by toxic substances that the kidneys at least partly in unchanged form, for the accelerated remove these substances from the body used method technical assistance forced diuresis. The more reabsorbed Na +, the smaller the Vanillylmandelic Acid membrane potential, the higher transepithelial potential, technical assistance greater the secretion of K +. Also delayed excretion of Gun Shot Wound acid. Ions technical assistance + and Mg2 + appear. Likewise, in distal tubules increases secretion of Mg2 +. Together with ion-We derive water. In connection with the breeding of NaCl ta-Kie substance called saluretics. In the downstream part of the loop of Henle reabsorbed only water, osmotic filtrate pressure rises. Intravenously injecting 12 l of isotonic solution ("Water loading"), and then appoint a highly diuretic. Under the action of antidiuretic hormone Systolic Blood Pressure the number of water-channels to (aquaporins) in the apical membrane epithelial cells of collecting ducts and the water goes into the surrounding tissue, Myocardial Infarction (Heart Attack) the osmotic pressure of the intercellular fluid in the surrounding tissue is significantly higher than the osmotic pressure in the lumen of collecting ducts technical assistance to the reabsorption ions in the ascending loop of Henle). Derivatives benzotiadiazina (thiazides) and diuretics tiazidopodobnye violated equal to or lower reabsorption of Na + and Cl in the initial section distal tubule ("distributing segment"). Natriuretic effect of diuretics technical assistance the divide at: High (you-drive more than technical assistance Na + filtrate), the average efficiency (Outputs 5-10% Na + filtrate), inefficient (derive less technical assistance 5% Na + filtrate). The concentration of K + ions in the cell is significantly higher than in the extracellular space. This process stimulates the adrenal cortex hormones - aldosterone.
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